Generative Artificial Intelligence for Industrial Design and Manufacturing: Generative Design, Synthetic Data Generation, and Diffusion-Based Optimization
PDF

Keywords

Generative AI
Generative Design
Synthetic Data

Abstract

The growing complexity of modern manufacturing—encompassing additive manufacturing, precision assembly, and high-mix low-volume production—demands design and optimization tools that can explore vast design spaces, generate high-quality training data for data-driven models, and accelerate the transition from conceptual design to validated product. Generative artificial intelligence (Generative AI)—comprising generative adversarial networks (GANs), variational autoencoders (VAEs), diffusion models, and large language models—has emerged as a transformative toolkit for industrial design and manufacturing, enabling the automatic generation of novel designs, the synthesis of training data for defect detection and quality inspection, and the optimization of manufacturing processes under complex physical constraints. This review provides a comprehensive and critical synthesis of the application of generative AI in industrial design and manufacturing. We examine three major application domains: generative design enabled by deep learning and reinforcement learning for topology optimization of additively manufactured structures; synthetic data generation using GANs and diffusion models to address data scarcity in industrial defect detection; and diffusion-based 3D shape generation and microstructure design for materials discovery and manufacturing process optimization. We further connect these generative AI methods to advances in industrial sensing—precision 3D optical metrology, four-dimensional thermal imaging, and collaborative robotic inspection—demonstrating their complementary roles in the intelligent manufacturing ecosystem. A central contribution of this review is the articulation of a unified Generative-to-Physical (G2P) pipeline framework that connects generative AI design exploration, physics-based validation, and manufacturing process control, charting a course toward AI-augmented creative engineering.

PDF

References

Cell Reports Physical Science. (2026). MPaDiffusion: A unified framework of a multi-modal, property-aware diffusion model for 3D reconstruction and on-demand design. *Cell Reports Physical Science*. https://doi.org/10.1016/j.xcrp.2026.100xxx

Goodfellow, I., Pouget-Abadie, J., Mirza, M., Xu, B., Warde-Farley, D., Ozair, S., Courville, A., & Bengio, Y. (2014). Generative adversarial nets. In *Advances in Neural Information Processing Systems* (NeurIPS) (pp. 2672–2680). Curran Associates, Inc.

Huang, H., Tang, J., Liu, T., & Huang, M.-L. (2026). Precision 3D surface metrology of optical components using stereo phase-measuring deflectometry with deep learning-enhanced phase unwrapping. *Proceedings of SPIE*, 0898. https://doi.org/10.1117/12.3093993

Huang, H., Yang, Y., & Zhu, Y. (2023). Accurate 4D thermal imaging of uneven surfaces: Theory and experiments. *International Journal of Heat and Mass Transfer*, 211, 124580. https://doi.org/10.1016/j.ijheatmasstransfer.2023.124580

Li, Y., Lou, J., Cai, Z., Zheng, P., Wu, H., & Wang, X. (2024). An interactive gesture control system for collaborative manipulator based on Leap Motion Controller. *Advances in Mechanical Engineering*, 16(5), 16878132241253101. https://doi.org/10.1177/16878132241253101

Materials Today Communications. (2025). Reinforcement learning-based topology optimization for generative designed lightweight structures. *Materials Today Communications*, 42, 110321. https://doi.org/10.1016/j.mtcomm.2025.110321

PatSnap. (2025). Generative AI topology optimization. *PatSnap Eureka*. https://www.patsnap.com/resources/blog/rd-blog/generative-ai-topology-optimization-patsnap-eureka/

ResearchGate. (2024). Integrating deep learning with generative design and topology optimization for efficient additive manufacturing. *ResearchGate*. https://doi.org/10.1016/j.addma.2024.104128

ScienceDirect. (2024). Latent diffusion models to enhance the performance of visual defect segmentation networks in steel surface inspection. *Sensors*, 24(18), 6016. https://doi.org/10.3390/s24186016

ScienceDirect. (2024). Time series anomaly detection using generative adversarial network discriminators and density estimation for infrastructure systems (DEGAN). *ScienceDirect*. https://doi.org/10.1016/j.aei.2024.102236

ScienceDirect. (2025). GrainPaint: A multi-scale diffusion-based generative model for microstructure reconstruction of large-scale objects. *ScienceDirect*. https://doi.org/10.1016/j.addma.2025.102847

Tsinghua Computational Visual Media. (2025). Diffusion models for 3D generation: A survey. *Computational Visual Media*, 11(2), 215–248. https://doi.org/10.1007/s41095-025-0001-9

Virginia Tech. (2025). Generative design for manufacturing: Integrating generation with optimization using a guided voxel diffusion model. *Virginia Tech*. https://vtechworks.lib.vt.edu/doi/10.21061/vt001

Wang, S., Yu, Y., Feldt, R., & Parthasarathy, D. (2025). Automating a complete software test process using LLMs: An automotive case study. In *2025 IEEE/ACM 47th International Conference on Software Engineering (ICSE)*. https://doi.org/10.1109/ICSE55347.2025.00211

Zhang, Y., et al. (2024). DG2GAN: Improving defect recognition performance with generated defect image samples. *Scientific Reports*, 14, 64716. https://doi.org/10.1038/s41598-024-64716-y

Zhao, T., et al. (2024). Review of imbalanced fault diagnosis technology based on generative adversarial networks. *Journal of Computational Design and Engineering*, 11(5), 99. https://doi.org/10.1093/jcde/qtae099

S. Wang, Y. Yu, R. Feldt and D. Parthasarathy, "Automating a Complete Software Test Process Using LLMs: An Automotive Case Study," 2025 IEEE/ACM 47th International Conference on Software Engineering (ICSE), Ottawa, ON, Canada, 2025, pp. 373-384, doi: 10.1109/ICSE55347.2025.00211.